カワバタ　テルエ   TERUE KAWABATA
  川端　輝江
   所属   栄養学部
   職種   教授
言語種別 英語
発行・発表の年月 2019/07
形態種別 研究論文（学術雑誌）
査読 査読あり
標題 Aging and FADS1 polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U-13C]linoleic acid.
執筆形態 共著
掲載誌名 Prostaglandins Leukot Essent Fatty Acids
掲載区分国外
巻・号・頁 148(1-8)
著者・共著者 Sasaki H, Sueyasu T, Tokuda H, Ito M, Kaneda Y, Rogi T, Kawashima H, Horiguchi S, Kawabata T, Shibata H.
概要 This study examined the effects of aging and FADS polymorphisms on LCPUFA biosynthetic capacity via direct quantification using [U-13C]linoleic acid. The area under the curve of the 13C-ARA concentration differed by FADS1 rs174547 polymorphism. Among C allele carriers, 13C-ARA formation was 32% lower in elderly than in young participants. LCPUFA biosynthetic capacity is regulated by FADS1 polymorphisms and decreased by aging in FADS1 C allele carriers.