カワバタ　テルエ   TERUE KAWABATA
  川端　輝江
   所属   栄養学部
   職種   教授
言語種別 英語
発行・発表の年月 2022/05
形態種別 研究論文（学術雑誌）
査読 査読あり
標題 Investigation of maternal diet and FADS1 polymorphism associated with long-chain polyunsaturated fatty acid compositions in human milk
執筆形態 共著
掲載誌名 Nutrients
掲載区分国外
巻・号・頁 14
著者・共著者 Niwa S, Kawabata T, Shoji K, Ogata H, Kagawa Y, Nakayama K, Yanagisawa Y, Iwamoto S, Tatsuta N, Asato K, Arima T, Yaegashi N, Nakai K
概要 We investigated the associations of LCPUFA compositions in human milk with maternal diet, with fatty acid delta-5 desaturase gene (FADS1) polymorphisms, and with gene-diet interactions. The composition of ARA showed significant gene-dietary interactions in multiple regression analysis, and the positive correlation between fish and shellfish intake and ARA composition in human milk was significant only in the CC genotype. Moreover, the factor most strongly associated with EPA and DHA composition in human milk was fish and shellfish intake. Therefore, it was suggested that increasing fish and shellfish intake in mothers may increase EPA and DHA composition in human milk, while increasing fish and shellfish intake in CC genotype mothers may lead to increased ARA composition in human milk.