ウスイ　テルユキ   Teruyuki USUI
  臼井　照幸
   所属   栄養学部
   職種   教授
言語種別 英語
発行・発表の年月 2006/06
形態種別 研究論文（学術雑誌）
標題 Isolation and identification of 5-methyl-imidazolin-4-one derivative as glyceraldehyde-derived advanced glycation end product
執筆形態 共著
掲載誌名 Bioscience Biotechnology, and Biochemistry
巻・号・頁 70,pp.1496-1498
著者・共著者 Teruyuki USUI,Hirihito WATANABE,Fumitaka HAYASE
概要 We isolated and identified the glyceraldehyde-derived advanced glycation product (AGE) formed from glyceraldehyde and Nα-acetylarginine. A major product was identified as Nα-acetyl-Nδ-(5-methyl-imidazolin-4-one-2-yl)-ornithine. The compound has been reported as methylglyoxal-derived AGE, MG-H1. This study suggests that MG-H1 is formed through both glyceraldehyde-related and methylglyoxal-related pathways. There is a possibility that MG-H1 becomes an index of injury to glyceraldehyde and methylglyoxal-related enzymes.