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女子栄養大学 教員紹介 |
ウスイ テルユキ
Teruyuki USUI 臼井 照幸 所属 栄養学部 職種 教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2008/02 |
形態種別 | 研究論文(学術雑誌) |
標題 | Formation of argpyrimidine in glyceraldehyde-related glycation |
執筆形態 | 共著 |
掲載誌名 | Bioscience Biotechnology, and Biochemistry |
巻・号・頁 | 71,pp.2465-2472 |
著者・共著者 | Teruyuki USUI,Mio Ohguchi,Hirohito WATANABE,Fumitaka HAYASE |
概要 | Three major glyceraldehyde-related advanced glycation end products (AGEs) were formed from a mixture of Nα-acetyllysine, Nα-acetylarginine, and glyceraldehyde. Two of the compounds were MG-H1 and GLAP, as previously reported, and the other compound was identified as Nα-acetyl-Nδ-(5-hydroxy-4,6-dimethyl-pyrimidin-2-yl)-ornithine, argpyrimidine (APN). APN is a modification product of arginine residue, but it did not form from glyceraldehyde with arginine residue. The coexistence of lysine residue was necessary to APN formation. |