ヒガサ　シヅ   Higasa Shizu
  日笠　志津
   所属   栄養学部
   職種   准教授
言語種別 英語
発行・発表の年月 2007/10
形態種別 研究論文（学術雑誌）
査読 査読あり
標題 Polymorphism of glutathione S-transferase P1 gene affects human vitamin C metabolism
執筆形態 共著
掲載誌名 Biochemical and Biophysical Research Communications
巻・号・頁 364(3),pp.708-713
総ページ数 null
著者・共著者 Shizu Higasa, Masaru Tsujimura, Mami Hiraoka, Kazuhiro Nakayama, Yoshiko Yanagisawa, Sadahiko Iwamoto, Yasuo Kagawa
概要 There are large inter-individual differences in the metabolism of vitamin C (VC), which is composed of both ascorbic acid (AsA) and dehydroascorbic acid (DAsA). At 24 h after administration of 1 mmol of VC to young women (n = 17; age, 21.0 ± 1.1 y), total VC excretion (46.7 ± 18.1 mg) by AA homozygotes of glutathione S-transferases P1 was greater (p < 0.0069) than that (28.2 ± 14.0 mg) by GA heterozygotes.
(My division can't explain clearly because of a joint research.)