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女子栄養大学 教員紹介 |
アカイ ショウジ
Akai Shoji 赤井 昭二 所属 栄養学部 職種 教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2001/05 |
形態種別 | 研究論文 |
査読 | 査読あり |
標題 | Novel Methods for synthesizing 2-Chloroaldehyde from Carbonyl Compounds and Converting It into 2-Hydroxyaldehyde Derivatives |
執筆形態 | 共著 |
掲載誌名 | Tetrahedron Lett. |
掲載区分 | 国外 |
出版社・発行元 | Elsevier |
巻・号・頁 | 42(21),pp.3625-3628 |
著者・共著者 | K. Sato, T. Sekiguchi, S. Akai |
概要 | 2-Chloroaldehyde derivs. were synthesized from carbonyl compds. with [chloromethyl (dimethyl)sulfonium trifluoromethanesulfonate,] and DBU in THF in good yields. Further, 2-chloroaldehyde derivs. were converted into the corresponding 2-hydroxyaldehydes by treating the derivs. with n-Bu4NOH in good yields with the inverted configuration. The stereochem. of all the products were detd. by NMR (NOE). |