ウスイ テルユキ   Teruyuki USUI
  臼井 照幸
   所属   栄養学部
   職種   教授
言語種別 英語
発行・発表の年月 2012/07
形態種別 研究論文(その他学術会議資料等)
標題 3-Deoxy-
xylosone-related Maillard reaction products
執筆形態 共著
掲載誌名 IMARS Highlights, (2012)
巻・号・頁 7,pp.3-4
著者・共著者 Teruyuki USUI
概要 3DX is a major alpha-dicarbonyl compound like as 3DG. Reactive 3DX may
induce protein glycation. Recent study revealed that pyrropyridine-like fluorescent
cross-linked product (3DX-pyrropyridine) was generated in the 3DX-related Maillard
reaction (unpublished data). The chemical structure of pyrropyridine and 3DXpyrropyridine
is shown in fig. 1. These compounds are furopyrrolopyridinium, and
show fluorescence (ex.370nm, em.460nm). 3DX-pyrropyridine was formed from 2
molecules of lysine residue as a pyrropyridine analog. 3DX was the major alphadicarbonyl
compound, and induces the AGEs formation. The 3DX-derived AGEs
might be formed in biological systems and foods.