アカイ ショウジ   Akai Shoji
  赤井 昭二
   所属   栄養学部
   職種   教授
言語種別 英語
発行・発表の年月 2003/05
形態種別 研究論文
査読 査読あり
標題 Practical synthesis of [1-13C]- and [6-13C]-D-galactose
執筆形態 共著
掲載誌名 Tetrahedron Lett.
掲載区分国外
出版社・発行元 Elsevier
巻・号・頁 44(26),pp.4903-4907
著者・共著者 K. Sato, S. Akai, M. Sakuma, M. Kojima, K. Suzuki
概要 The chem. synthesis of 13C-labeled D-galactose as useful mol. probes for studying the conformation of oligosaccharides attached to proteins was performed. The method for synthesizing the title labeled compds. was newly developed via the corresponding 1-ene and 5-ene compds. derived from 1,2:5,6-di-O-isopropylidene-alpha-D-galactofuranose by considering the efficient introduction of the atom. All protons of galactose from H-1 to H-6 were obsd. by the HMQC-HOHAHA technique using 1:1 mixts. of Me [1-13C]- and [6-13C]-beta-D-galactopyranoside, which were prepd. from the title compds.