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女子栄養大学 教員紹介 |
アカイ ショウジ
Akai Shoji 赤井 昭二 所属 栄養学部 職種 教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2007/05 |
形態種別 | 研究論文 |
査読 | 査読あり |
標題 | The first total synthesis of telephiose A |
執筆形態 | 共著 |
掲載誌名 | Tetrahedron Lett. |
掲載区分 | 国外 |
出版社・発行元 | Elsevier |
巻・号・頁 | 48(20),pp.3745-3748 |
著者・共著者 | K. Sato, K. Sakai, K. Tsushima, S. Akai |
概要 | The first total synthesis of telephiose A, a novel trisaccharide ester having two acetyl groups and two benzoyl groups, was achieved by using glucosyl donor I and sucrose deriv. acceptor. The crucial key step was the stereoselective construction of the -D-glucosidic linkage featuring the neighboring group participation of the 2-O-N-phenylcarbamoyl group of donor I, which can be selectively deprotected in the presence of acetyl and benzoyl groups. Donor I was prepd. from D-glucose in eight steps (33% yield), whereas acceptor sucrose deriv. was prepd. from sucrose in six steps (35% yield). ... Most-Accessed Articles_ April-June 2007 - Tetrahedron Letters |