サイトウ　マサタカ   Masataka Saito
  西塔　正孝
   所属   栄養学部
   職種   教授
言語種別 英語
発行・発表の年月 2024/05
形態種別 研究論文
査読 査読あり
標題 Characterization of Fish Skin Hydrolysates Exhibiting Dipeptidyl Peptidase IV Inhibitory Activity
執筆形態 共著
掲載誌名 Indonesian Food and Nutrition Progress
掲載区分国外
巻・号・頁 21(1),pp.1-10
担当区分 最終著者,責任著者
著者・共著者 Honoka Miyamoto, Erwina Safitri, Takeshi Nagai, Masataka Saito
概要 Dipeptidyl peptidase IV (DPP-IV) inhibitors are antidiabetic drugs that can lower blood sugar levels. There are still few reports on the DPP-IV inhibitory activity of peptides obtained from discarded fish skin. Therefore, we prepared various enzymatic hydrolysates using the skins of six fish species and investigated their DPP-IV inhibitory effects. As a result, it was found that the DPP-IV inhibitory activity of yellowtail hydrolysate by Alcalase was higher than that of other enzymes. In addition, the IC50 after ethanol fractionation was found to be lower in yellowtail and eel skin hydrolysate. The DPP-IV inhibitory peptide obtained from fish skin has the potential to be applied as a food material to various food products.