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	(Last updated : 2026-01-14 18:48:31)   Hisanori Katoh    Faculty of Nutrition    Professor
■ E-Mail Address
■ Education 1. 1980/04～1984/03 Department of Applied Biological Chemistry, Faculty of Agriculture, The University of Tokyo, Graduated, 2. 1984/04～1986/03 〔Master degree program〕 Department of Applied Biological Chemistry, Graduate School, Division of Agriculture, The University of Tokyo, Completed, MS 3. 1986/04～1988/11 〔Doctoral course〕 Department of Applied Biological Chemistry, Graduate School, Division of Agricultural Science, The University of Tokyo, Unfinished course 4. 1990/10/08 Degree Acquisition The University of Tokyo,
■ Career 1. 1988/11～1993/03 The University of Tokyo Faculty of Agriculture Research Assistant 2. 1993/04～1999/03 Utsunomiya University Faculty of Agriculture Associate Professor 3. 1991/04～1993/03 National Institutes of Health Diabetes Branch Guest Reseacher 4. 1999/04～2009/05 The University of Toykyo Graduate School of Agricultural and Life Sciences Associate Professor 5. 2009/06～2017/05 The University of Toykyo Organization for Interdisciplinary Research Projects Project Professor 6. 2017/06～2023/04 The University of Tokyo Graduate School of Agricultural and Life Sciences Project Professor 7. 2023/04～ Kagawa Nutrition University Faculty of Nutrition Professor 5 display All display(7)
■ Courses Previously Taught 1. Biochemistry（Kagawa Nutrition University） 2. General Lecture of Nutrition（Graduate School, Kagawa Nutrition University）
■ Research Interests/Keywords Food sciences, Genome biology, Nutrition science and health science, Molecular biology
■ Publications 1. Journal Articles Dietary eggshell membrane modulates gut microbiota and alleviates AOM/DSS-induced colonic inflammation in mice  (Collaboration)  2026 2. Journal Articles Offspring metabolic programming via the maternal diet increases susceptibility to metabolic dysregulation.  (Collaboration)  2025/08 3. Journal Articles Validity of digital photographic images for dietary assessment of participants with low frequency of home-made meal intake.  (Collaboration)  2025 4. Journal Articles Eggshell membrane, a resistant protein, possesses prebiotic-like properties in improving gut microbiota composition and gut-liver axes in chronologically aged C57BL/6J male mice.  (Collaboration)  2024/12 5. Journal Articles Genome-wide association meta-analysis identifies two novel loci associated with dental caries  (Collaboration)  2024 6. Journal Articles Alteration and reprogramming of renal Ptger1 DNA methylation induced by maternal protein restriction in hypertensive rat offspring.  (Collaboration)  2023 7. Journal Articles A study on the association between antiobesity effects of lactoferrin and genetic variations.  (Collaboration)  2023 8. Journal Articles Effects of thyme (Thymus vulgaris L.) essential oil on aging-induced brain inflammation and blood tlomere attrition in ahronologically aged C57BL/6J mice.  (Collaboration)  2023 9. Journal Articles Effects of turmeric extract on age-related skeletal muscle atrophy in senescence-accelerated mice.  (Collaboration)  2023 10. Journal Articles Exogenous Penicillium camemberti lipase preparation exerts prebiotic-like effects by increasing fecal Bifidobacterium and Lactobacillus abundance in rats.  (Collaboration)  2023 11. Journal Articles Postnatal nutrition environment reprograms renal DNA methylation patterns in offspring of maternal protein-restricted stroke-prone spontaneously hypertensive rats  (Collaboration)  2023 12. Journal Articles Ketone-loading as a novel sports nutrition strategy: Chronic ketone supplementation elicits further favorable metabolic changes in keto-adapted mice.  (Collaboration)  2023 13. Journal Articles Ketogenic diet, ketone bodies, inflammation and mood disorder: Clinical evidence and potential mechanism.  (Collaboration)  2023 14. Journal Articles Transcriptome and methylome profiling in rat skeletal muscle: Impact of post-weaning protein restriction.  (Collaboration)  2022 15. Journal Articles Suppressive effects of turmeric extract on muscle atrophy in dexamethasone-treated mice and myotubes.  (Collaboration)  2022 16. Journal Articles Association between dietary behaviors and BMI stratified by sex and the ALDH2 rs671 polymorphism in Japanese adults.  (Collaboration)  2022 17. Journal Articles ATF4-dependent hsa-miR-663a transcription mediates mTORC1/p70S6K1 signaling under leucine deprivation  (Collaboration)  2022 18. Journal Articles Comprehensive miRNA and DNA microarray analysis reveal the response of hepatic miR-203 and its target gene to protein malnutrition in rats  (Collaboration)  2022 19. Journal Articles Dietary eggshell membrane powder improves survival rate and ameliorates gut dysbiosis in interleukin-10 knockout mice.  (Collaboration)  2022 20. Journal Articles Effect of heat-moisture treated brown rice crackers on postprandial flow-mediated dilation in adults with mild endothelial dysfunction.  (Collaboration)  2022 21. Journal Articles Eggshell membrane modulates gut microbiota to prevent murine pre-cachexia through suppression of T helper cell differentiation  (Collaboration)  2022 22. Journal Articles iTRAQ-based quantitative proteomics reveals the energy metabolism alterations induced by chlorogenic acid in HepG2 cells.  (Collaboration)  2022 23. Journal Articles Laurel attenuates dexamethasone-induced skeletal muscle atrophy in vitro and in a rat model.  (Collaboration)  2022 24. Journal Articles Maternal protein restriction and post-weaning high-fat feeding alter plasma amino acid profiles and hepatic gene expression in mice offspring  (Collaboration)  2022 25. Journal Articles Precision nutrition: A review of current approaches and future endeavors.  (Collaboration)  2022 26. Journal Articles The potential roles of probiotics, resistant starch, and resistant proteins in ameliorating inflammation during aging (inflammaging).  (Collaboration)  2022 27. Journal Articles A comparison of gene expression profiles of rat tissues after mild and short-term calorie restrictions.  (Collaboration)  2021 28. Journal Articles Effects of eggshell membrane on keratinocyte differentiation and skin aging in vitro and in vivo.  (Collaboration)  2021 29. Journal Articles Amaranth supplementation ameliorates high-fat diet-induced dyslipidemia and deterioration of gut microbiota structure in mice.  (Collaboration)  2021 30. Journal Articles Maternal protein restriction induces renal AT2R promoter hypomethylation in salt-sensitive, hypertensive rats.  (Collaboration)  2021 31. Journal Articles Zeolite-containing mixture alleviates microbial dysbiosis in dextran sodium sulfate induced colitis in mice.  (Collaboration)  2021 32. Journal Articles A Genome-wide association study identifies the association between the 12q24 locus and black tea consumption in Japanese populations.  (Collaboration)  2020 33. Journal Articles Transcriptional activation of Chac1 and other Atf4-target genes induced by extracellular L-serine depletion is negated with glycine consumption in Hepa1-6 hepatocarcinoma cells.  (Collaboration)  2020 34. Journal Articles Low-arginine and low-protein diets induce hepatic lipid accumulation through different mechanisms in growing rats.  (Collaboration)  2020 35. Journal Articles Disruption of insulin receptor substrate-2 impairs growth but not insulin function in rats.  (Collaboration)  2020 36. Journal Articles Strong association between the 12q24 locus and sweet taste preference in the Japanese population revealed by genome-wide meta-analysis.  (Collaboration)  2020 37. Journal Articles Eggshell membrane powder lowers plasma triglyceride and liver total cholesterol by modulating gut microbiota and accelerating lipid metabolism in high-fat diet-fed mice.  (Collaboration)  2020 38. Journal Articles A translation repressor, 4E-BP1, regulates the triglyceride level in rat liver during protein deprivation.  (Collaboration)  2020 39. Journal Articles Integrated omics profiling of dextran sodium sulfate-induced colitic mice supplemented with Wolfberry (Lycium barbarum)  (Collaboration)  2020 40. Journal Articles GWAS of habitual coffee consumption reveals a sex difference in the genetic effect of the 12q24 locus in the Japanese population.  (Collaboration)  2019 41. Journal Articles Identification of the 12q24 locus associated with fish intake frequency by genome-wide meta-analysis in Japanese populations.  (Collaboration)  2019 42. Journal Articles Low-protein diet enhances adiponectin secretion in rats.  (Collaboration)  2019 43. Journal Articles Maternal protein restriction alters the renal ptger1 DNA methylation state in SHRSP offspring.  (Collaboration)  2018 44. Journal Articles Enhanced vulnerability to oxidative stress and induction of inflammatory gene expression in 3-phosphoglycerate dehydrogenase-deficient fibroblasts.  (Collaboration)  2018 45. Journal Articles Branched-chain amino acid supplementation restores reduced insulinotropic activity of a low-protein diet through the vagus nerve in rats  (Collaboration)  2017 46. Journal Articles Zeolite-containing mixture supplementation ameliorated dextran sodium sulphate-induced colitis in mice by suppressing the inflammatory bowel disease pathway and improving apoptosis in colon mucosa.  (Collaboration)  2017 47. Journal Articles Eggshell membrane powder ameliorates intestinal inflammation by facilitating the restitution of epithelial injury and alleviating microbial dysbiosis.  (Collaboration)  2017 48. Journal Articles Acerola (Malpighia emarginata DC.) juice intake suppresses the UVB-induced skin pigmentation in SMP30/GNL knockout hairless mice  (Collaboration)  2017 49. Journal Articles Comparative integrated omics approach sterically understanding hepatic metabolic dynamics in mouse model.  (Collaboration)  2017 50. Journal Articles Lactoferrin interacts with bile acids and increases fecal cholesterol excretion in rats.  (Collaboration)  2017 51. Journal Articles Dietary genistein prevents denervation-induced muscle atrophy in rodents via effects on estrogen receptor-alpha  (Collaboration)  2016 52. Journal Articles Supplemental arginine above the requirement during suckling causes obesity and insulin resistance in rats.  (Collaboration)  2016 53. Journal Articles Adaptive response to L-serine deficiency is mediated by p38 MAPK activation via deoxysphinganine in normal fibroblasts.  (Collaboration)  2016 54. Journal Articles Enteric lactoferrin attenuates the development of high-fat and high-cholesterol diet-induced hypercholesterolemia and atherosclerosis in Microminipigs  (Collaboration)  2017 55. Journal Articles Down regulation of asparagine synthetase and 3-phosphoglycerate dehydrogenase, and the up-regulation of serine dehydratase in rat liver from intake of excess amount of leucine are not related to leucine-caused amino acid imbalance.  (Collaboration)  2015 56. Journal Articles Identification of the flavonoid luteolin as a repressor of the transcription factor hepatocyte nuclear factor 4alpha.  (Collaboration)  2015 57. Journal Articles Rapid increase of fibroblast growth factor 21 under protein malnutrition and its impact on growth and lipid metabolism.  (Collaboration)  2015 58. Journal Articles Lactoferrin attenuates fatty acid-induced lipotoxicity via Akt signaling in hepatocarcinoma cells.  (Collaboration)  2015 59. Book/Book Chapter Chapter 3: The comprehensive understanding of anti-diabetic and anti-obesity effects of coffee intake via nutrigenomics  (Collaboration)  2015 60. Journal Articles Eggshell membrane ameliorates hepatic fibrogenesis in human C3A cells and rats through changes in PPARγ-Endothelin 1 signaling  (Collaboration)  2014 61. Journal Articles Multi-faceted integrated omics analysis revealed Parsley (Petroselinum crispum) as a novel dietary intervention in dextran sodium sulphate induced colitic mice.  (Collaboration)  2014 62. Journal Articles Beneficial effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in the prevention of the onset of Type 2 diabetes and NAFLD in high fructose-fed rats  (Collaboration)  2014 63. Journal Articles Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter Niemann-Pick C1-like 1 in Caco-2 cells and rats.  (Collaboration)  2014 64. Journal Articles Coffee intake mitigated inflammation and obesity-induced insulin resistance in skeletal muscle of high-fat diet-induced obese mice.  (Collaboration)  2014 65. Journal Articles Tissue-specific effects of protein malnutrition on insulin signaling pathway and lipid accumulation in growing rats.  (Collaboration)  2014 66. Journal Articles An integrated multi-omics study revealed metabolic alterations underlying the effects of coffee consumption.  (Collaboration)  2014 67. Journal Articles Protective effects of acetaminophen on ibuprofen-induced gastric mucosal damage in rats with associated suppression of matrix metalloproteinase.  (Collaboration)  2014 68. Journal Articles Coffee intake down-regulates the hepatic gene expression of peroxisome proliferator-activated receptor gamma in C57BL/6J mice fed a high-fat diet  (Collaboration)  2014 69. Book/Book Chapter Identification of branched amino acids; Underlying molecular pathways using transcriptomics analysis: Application to cirrhosis.  (Collaboration)  2014 70. Book/Book Chapter Melatonin: its microbicidal propertiesand clinical applications.  (Collaboration)  2014 71. Journal Articles Transcriptional profiling in rats and an ex vivo analysis implicate novel beneficial function of egg shell membrane in liver fibrosis.  (Collaboration)  2013 72. Journal Articles Potent lipolytic activity of lactoferrin in mature adipocytes.  (Collaboration)  2013 73. Journal Articles Adverse effects of excessive leucine intake depend on dietary protein intake: A transcriptomic analysis to identify useful biomarkers.  (Collaboration)  2013 74. Journal Articles DNA microarray analysis identified molecular pathways mediating the effect of the supplementation of branched amino acids on CCl4-induced cirrhosis in rats.  (Collaboration)  2013 75. Journal Articles Bovine lactoferrin reduces visceral fat and liver triglycerides in ICR mice.  (Collaboration)  2012 76. Journal Articles Enhanced effect of daytime restricted feeding on the circadian rhythm of streptozotocin-induced type 2 diabetic rats.  (Collaboration)  2012 77. Journal Articles Role of the renin-angiotensin-aldosterone system in the enhancement of salt sensitivity caused by prenatal protein restriction in stroke-prone spontaneously hypertensive rats.  (Collaboration)  2012 78. Journal Articles Regulatory mechanism for the stimulatory action of genistein on glucose uptake in vitro and in vivo.  (Collaboration)  2012 79. Journal Articles Evaluation of the antioxidant potential of Chinese parsley (Coriandrum sativum) as compared with a synthetic antioxidant in diet.  (Collaboration)  2012 80. Journal Articles Antioxidant potential of Western parsley (Petroselinum crispum) extract and its effects on oxidative stabilities of food during storage.  (Collaboration)  2012 81. Journal Articles An optimized method for the determination of free L-cysteine in rat plasma by high-performance liquid chromatography using the derivatization reagent 4-aminosulfonyl-7-fluoro-2,1,3-benzoxadiazole.  (Collaboration)  2011 82. Journal Articles Significant dissociation of expression patterns of the basic helix-loop-helix transcription factors Dec1 and Dec2 in rat kidney.  (Collaboration)  2011 83. Journal Articles Differential roles of breakfast and supper in rats of a daily three-meal schedule upon circadian regulation and physiology.  (Collaboration)  2011 84. Journal Articles Mild caloric restriction up-regulates the expression of prohibitin: A proteome study.  (Collaboration)  2011 85. Journal Articles Effects of pepsin and trypsin on the anti-adipogenic action of lactoferrin against pre-adipocytes derived from rat mesenteric fat.  (Collaboration)  2011 86. Journal Articles Omics and integrated omics for the promotion of food and nutrition science.  (Single)  2011 87. Journal Articles Dietary protein deprivation up-regulates insulin signaling and inhibits gluconeogenesis in rat liver.  (Collaboration)  2010 88. Journal Articles Feeding-induced rapid resetting of the hepatic circadian clock is associated with acute induction of Per2 and Dec1 transcription in rats  (Collaboration)  2010 89. Journal Articles Dietary iron deficiency induces a variety of metabolic changes and even apoptosis in rat liver: a DNA microarray study.  (Collaboration)  2010 90. Journal Articles Effect of mild restriction of food intake on gene expression profile in the liver of young rats: reference data for in vivo nutrigenomics study.  (Collaboration)  2010 91. Journal Articles Regulation of circadian gene expression in the kidney by light and food cues in rats.  (Collaboration)  2010 92. Journal Articles Effect of fasting on the peripheral circadian gene expression in rats.  (Collaboration)  2010 93. Journal Articles Melatonin in septic shock: Some recent concepts.  (Collaboration)  2010 94. Book/Book Chapter Genomics applied to nutrients and functional foods in Japan: State of the art  (Collaboration)  2010 95. Journal Articles Sardine peptide with angiotensin I converting enzyme inhibitory activity improves glucose tolelance in stroke-prone spontaneously hypertensive rats.  (Collaboration)  2009 96. Journal Articles Differential resetting process of circadian gene expression in rat pineal glands after the reversal of the light/dark cycle via a 24-h light or dark period transition.  (Collaboration)  2009 97. Journal Articles Qualitative PCR methods for detecting major food allergens (peanut, soybean, and wheat) by using internal transcribed spacer region.  (Collaboration)  2009 98. Journal Articles Light and food signals cooperate to entrain the rat pineal circadian system.  (Collaboration)  2008 99. Journal Articles Opposite effects of PU.1 on mast cell stimulation.  (Collaboration)  2008 100. Journal Articles Effects of light cues on re-entrainment of the food-dominated peripheral clocks in mammals.  (Collaboration)  2008 101. Journal Articles Up-regulation of genes related to the ubiquitin-proteasome system in the brown adipose tissue of 24 h-fasted rats.  (Collaboration)  2008 102. Journal Articles Qualitative and quantitative PCR methods for detecting food allergens by using internal transcribed spacer region.  (Collaboration)  2008 103. Journal Articles Nutrigenomics: the cutting edge and Asian perspectives.  (Single)  2008 104. Journal Articles A novel PCR method for quantification of buckwheat using a unique internal standard material.  (Collaboration)  2006 105. Journal Articles Gene expression analysis of the anti-obesity effect by apple polyphenols in rats fed a high fat diet or a normal diet.  (Collaboration)  2006 106. Journal Articles Safety evaluation of hypoallergenic wheat flour using a DNA microarray.  (Collaboration)  2006 107. Journal Articles A nutrigenomics database - Integrated repository for publications and associated microarray data in nutrigenomics research.  (Collaboration)  2005 108. Journal Articles Disruption of the availability of amino acids induces a rapid reduction of serine phosphorylation of insulin receptor substrate-1 in vivo and in vitro.  (Collaboration)  2005 109. Journal Articles Intake of soy protein isolate alters hepatic gene expression in rats.  (Collaboration)  2005 110. Journal Articles PCR method for detecting trace amounts of buckwheat (Fagopyrum spp.) in food.  (Collaboration)  2005 111. Journal Articles A perspective on DNA microarray technology in food and nutritional science.  (Collaboration)  2005 112. Journal Articles Transcriptomics and metabolomics of dietary leucine excess.  (Collaboration)  2005 113. Journal Articles Dietary protein deprivation decreases the serine phosphorylation of insulin receptor substrate-1 in rat skeletal muscle.  (Collaboration)  2004 114. Journal Articles DNA microarray analyses of the effects of dietary proteins  (Collaboration)  2004 115. Journal Articles Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16.  (Collaboration)  2003 116. Journal Articles Dietary protein is a potent regulator of the hyaluronan synthase gene in rat skin.  (Collaboration)  2003 117. Journal Articles Evaluation of the effects of the dietary intake of proteins and amino acids by DNA microarray technology.  (Collaboration)  2003 118. Journal Articles Response of the IGF system to vitamin A depletion and repletion in rats.  (Collaboration)  2002 119. Journal Articles Dietary protein quantity and quality affect rat hepatic gene expression.  (Collaboration)  2002 120. Journal Articles Molecular basis of the alteration in skin-collagen metabolism in response to in vivo dexamethasone treatment: Effects on syntheses of collagen type I and III, collagenase, and TIMPs.  (Collaboration)  2002 121. Journal Articles Intracerebroventricular injection of glucagon-like peptide-1 decreases monoamine concentrations in the hypothalamus of chicks.  (Collaboration)  2002 122. Journal Articles Effects of protein deprivation on alpha1(I) and alpha1(III) collagen and its degrading system in rat skin  (Collaboration)  2002 123. Journal Articles Molecular cloning and circadian regulation of cryptochrome genes in the Japanese quail (Coturnix coturnix japonica).  (Collaboration)  2002 124. Journal Articles Regulation of hydroxyindole-O-methyltransferase gene expression in Japanese quail (Coturnix coturnix japonica).  (Collaboration)  2001 125. Journal Articles Up-regulation of upstream stimulatory factors by protein malnutrition and its possible role in regulation of the IGF-binding protein-1 gene.  (Collaboration)  2001 126. Journal Articles Differential regulation of IGFBP-2 and IGFBP-5 gene expression by vitamin A status in Japanese quail.  (Collaboration)  2001 127. Journal Articles Retinoid nutritional status differently affects the expression of quail RARbeta isoform transcripts in a tissue-specific manner.  (Collaboration)  2001 128. Journal Articles Vitamin A deficiency reduces IGF-I gene expression and increases IGF-I receptor and insulin receptor gene expression in tissues of Japanese quail (Coturnix coturnix japonica).  (Collaboration)  2001 129. Journal Articles Developmental changes in the mRNA levels of IGF-I and its related genes in the reproductive organs of Japanese quail (Coturnix coturnix japonica)  (Collaboration)  2001 130. Journal Articles Cloning of cDNAs encoding quail (Coturnix coturnix japonica) retinoic acid receptor beta isoforms and changes in their gene expression during gonadotropic growth.  (Collaboration)  2001 131. Journal Articles Extracellular norepinephrine in the medial hypothalamus increases during feeding in chicks: A microdialysis study.  (Collaboration)  2000 132. Journal Articles Gene expression of the three members of hepatocyte nuclear factor-3 is differentially regulated by nutritional and hormonal factors.  (Collaboration)  2000 133. Journal Articles Retinoic acid accelerates the development of reproductive organs and egg production in Japanese quail (Coturnix coturnix japonica).  (Collaboration)  2000 134. Journal Articles The tyrosine kinase activity of the chicken insulin receptor is similar to that of the human insulin receptor.  (Collaboration)  2000 135. Journal Articles Feeding a lysine-free diet decreases food intake without changes in hypothalamic monoamine concentrations in growing chickens.  (Collaboration)  1999 136. Journal Articles Regulation of the expression of serotonine N-acetyltransferase gene in Japanese quail (Coturnix japonica): (II) Effect of vitamin A deficiency.  (Collaboration)  1999 137. Journal Articles Regulation of the expression of serotonine N-acetyltransferase gene in Japanese quail (Coturnix japonica): (I) Rhythmic pattern and effect of light.  (Collaboration)  1999 138. Journal Articles Decrease of the obese gene expression in bovine subcutaneous adipose tissue by fasting.  (Collaboration)  1998 139. Journal Articles Circadian rhythm of pineal melatonin contents in silky chicks.  (Collaboration)  1998 140. Journal Articles Vitamin A deficiency reduces the responsiveness of pineal gland to light in Japanese quail (Coturnix japonica).  (Collaboration)  1998 141. Journal Articles Diurnal changes in the enzyme activity and the messenger RNA level of pineal serotonin N-acetyltransferase in normal and hereditary microphthalmic rats.  (Collaboration)  1997 142. Journal Articles Analyses of serotonin N-acetyltransferase mRNA content in rat pineal grand and testis by an improved assay system - Micro lysate assay.  (Collaboration)  1997 143. Journal Articles Retinoic acid accelerates the testicular maturation in Japanese quail.  (Collaboration)  1997 144. Journal Articles Differential phosphorylation of pp120 by insulin and insulin-like growth factor-1 receptors: Role for the C-terminal domain of the beta-subunit.  (Collaboration)  1997 145. Journal Articles Nutritional regulation of insulin-like growth factor-I receptor mRNA levels in growing chickens.  (Collaboration)  1996 146. Book/Book Chapter Nutritional regulation of gene expression of IGFs and their related proteins.  (Collaboration)  1996 147. Journal Articles Single tyrosine substitution in the insulin-like growth factor I receptor inhibits ligand-induced receptor autophosphorylation and internalization, but not mitogenesis.  (Collaboration)  1995 148. Journal Articles Dissociation of mitogenesis and transforming activity by C-terminal truncation of the insulin-like growth factor-I receptor.  (Collaboration)  1995 149. Journal Articles Mutation of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase domain of the IGF-I receptor abolishes autophosphorylation but does not eliminate biologic function.  (Collaboration)  1995 150. Journal Articles Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation.  (Collaboration)  1994 151. Journal Articles Role of the carboxyl-terminal domains of the insulin and insulin-like growth factor I receptor function.  (Collaboration)  1994 152. Journal Articles Essential role of tyrosine residues 1131, 1135 and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action.  (Collaboration)  1994 153. Book/Book Chapter Pathological alterations in various components of the insulin-like growth factor signalling system.  (Collaboration)  1994 154. Journal Articles Effect of protein nutrition on the messenger RNA content of insulin-like growth factor binding protein-1 in liver and kidney of rats.  (Collaboration)  1993 155. Journal Articles Paradoxical biological effects of overexpressed insulin-like growth factor-I receptors in Chinese hamster ovary cells.  (Collaboration)  1993 156. Journal Articles Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of IGF-I mimetic antibody (alphaIR-3).  (Collaboration)  1993 157. Book/Book Chapter Insulin-like growth factor receptors - Implications for nervous system function.  (Collaboration)  1993 158. Book/Book Chapter Divergence of insulin and insulin-like growth factor-I signalling pathways.  (Collaboration)  1993 159. Journal Articles Effects of dexamethasone on the production of insulin-like growth factor-I and insulin-like growth factor binding proteins in primary cultures of rat hepatocytes.  (Collaboration)  1992 160. Journal Articles Effect of dietary proteins on insulin-like growth factor-I (IGF-I) messenger ribonucleic acid content in rat liver.  (Collaboration)  1992 161. Journal Articles Insulin-like growth factors.  (Collaboration)  1992 162. Journal Articles Distribution of messenger RNAs of insulin-like growth factor (IGF)-binding proteins-1 and -3 between parenchymal and nonparencymal cells in rat liver.  (Collaboration)  1991 163. Journal Articles Effect of protein deprivation on insulin-like growth factor-binding proteins in rats.  (Collaboration)  1991 164. Journal Articles The effect of quantity and nutritional quality of dietary proteins on plasma concentration of insulin-like growth factor binding proteins (IGFBP) and the saturability of IGFBP with endogenous IGF-I.  (Collaboration)  1991 165. Journal Articles Effect of dietary proteins on the plasma immunoreactive insulin and insulin-like growth factor-I/somatomedin C concentration in the rat.  (Collaboration)  1990 166. Journal Articles Correlation between the urinary excretion of acid soluble peptides, fractional synthesis rate of whole body proteins, and plasma insulin-like growth factor-I/somatomedin C concentration in the rat.  (Collaboration)  1990 167. Journal Articles Evidence of introduction by molecular cloning of artificial inverted sequence at the 5' terminus of the sense strand of rat insulin-like growth factor-I cDNA.  (Collaboration)  1990 168. Journal Articles A new cDNA clone relating to larger molecular species of rat insulin-like growth factor-I mRNA.  (Collaboration)  1990 169. Journal Articles The effects of bestatin, a microbial aminopeptidase inhibitor, on epidermal growth factor- induced DNA synthesis and cell division in primary cultured hepatocytes of rats.  (Collaboration)  1989 170. Journal Articles Microinjection of endogenous proteins into primary cultures of rat hepatocytes and the degradation of the injected proteins.  (Collaboration)  1989 171. Journal Articles Degradation of endogenous proteins and internalized asialofetuin in primary cultured hepatocytes of rats.  (Collaboration)  1989 172. Book/Book Chapter Dietary and hormonal factors affecting the mRNA level of IGF-I in rat liver in vivo and in primary cultures of rat hepatocytes.  (Collaboration)  1989 173. Book/Book Chapter Microinjection of endogenous and exogenous proteins into primary cultured hepatocytes and degradation of the injected proteins.  (Collaboration)  1989 174. Book/Book Chapter Mechanism and rate of degradation of short- and long-lived proteins in primary cultured rat hepatocytes.  (Collaboration)  1989 175. Journal Articles Intermediate peptides of insulin degradation in liver and cultured hepatocytes of rats.  (Collaboration)  1988 176. Journal Articles Further studies on the nutritional factors affecting the urinary excretion of acid-soluble peptides in rats.  (Collaboration)  1988 177. Journal Articles Mode of action of bestatin and leupeptin to induce the accumulation of acid soluble peptides in rat liver in vivo and the properties of the accumulated peptides. The important role of bestatin- and leupeptin- sensitive proteases in the protein degradation pathway in vivo.  (Collaboration)  1987 178. Journal Articles Bestatin, a microbial aminopeptidase inhibitor inhibits DNA synthesis induced by insulin or epidermal growth factor in primary cultured rat hepatocytes.  (Collaboration)  1985 5 display All display(178)
■ Memberships 1. 1990/04～ Japan Society of Nutrition and Food Science 2. 2002/05～2004/05 ∟ Trustee 3. 2008/05～2014/05 ∟ Trustee 4. 2016/05～2018/05 ∟ Trustee 5. 2018/05～2020/05 ∟ Vice President 6. 2020/05～2022/05 ∟ President 7. 2007～ Japanese Society for Amino Acid Sciences 8. 2013/10～2023/08 Organizing Committee of the 22nd IUNS-International Congress of Nutrition 9. 2013/10～2023/08 ∟ Chair 5 display All display(9)
■ Prizes,Honors,and Awards 1. 2024/09 The Japanese Soceity for Amino Acid Sciences Award for Distinguished Investigator 2. 2023/09 Fellow Award of Federation of Asian Nutrition Societies 3. 2020/12 Merit Award of Asia Pacific Nutrigenomics & Nutrigenetics Organisation 4. 2015/05 Japan Society of Nutrition and Food Science Award for Excellence in Research 5. 1997/03 The Japan Bioscience, Biotechnology and Agrochemistry Society Award for the Encouragement of Young

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